ZNF259 antibody - C-terminal region (ARP38400_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

ZPR1 zinc finger

Gene Aliases

ZNF259

Gene ID

8882

Swiss Prot

O75312

Accession Number

NP_003895

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF259

Target

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; P3H1; FKBP10; RPRD1B; OSGEP; PPME1; SZRD1; ARIH1; HSPBP1; ACTR2; ACTR3; ARPC4; UBA2; TOM1L1; OGT; SURF2; PPP1R7; LPP; HSF1; AGFG1; HNRNPF; BAG1; ALAD; MPP3; SRXN1; NUDCD2; UBL7; THOC7; KLC2; UBQLN4; UFM1; UFC1; UBXN1; UHRF1; PHPT1; TES; UBXN7; HYPK

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 85%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

459

NCBI Gene Symbol

ZPR1

Host or Source

Rabbit

Protein Name

Zinc finger protein ZPR1

Gene Name URL

ZPR1

Nucleotide Accession Number

NM_003904

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