ZFP36 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Zinc finger protein 36, C3H type, homolog (mouse)

Gene Aliases

TTP, G0S24, GOS24, TIS11, NUP475, zfp-36, RNF162A

Gene ID

7538

Swiss Prot

P26651

Accession Number

NP_003398

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ZFP36

Target

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.

Partner Proteins

YWHAB; PPP2CA; DNAJB1; DCP1B; DHX36; PRR5L; XRN1; UBC; TRAF2; EXOSC6; UPF2; EXOSC8; YWHAQ; TNF; DCP2; EDC3; DCP1A; EDC4; CDK6; APP; LIN28A; SH3KBP1; PABPC1; NCL; MAP3K4; HSPA4; HDAC7; HDAC3; NFKB1; HOXC9; HDAC1; CCDC85B; MAPKAPK2; YWHAG; SFN; HMGB1; NUP21

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGSDSPVFE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

326

NCBI Gene Symbol

ZFP36

Host or Source

Rabbit

Protein Name

Tristetraprolin

Gene Name URL

ZFP36

Nucleotide Accession Number

NM_003407

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS623266-01 0.1 mL

Zeranol

Ask

View Details

MBS623266-02 5x 0.1 mL

Zeranol

Ask

View Details

TS407122P5 25 Slides

Claudin 5 (CLDN5) CytoSection

Ask

View Details

39014176 3x 5 nmol

RGD1307704 siRNA Oligos set (Rat)

Ask

View Details

MBS1169720-01 0.02 mg (E-Coli)

Recombinant Shewanella baltica Cell division protein ZapB (zapB)

Ask

View Details

MBS1169720-02 0.1 mg (E-Coli)

Recombinant Shewanella baltica Cell division protein ZapB (zapB)

Ask

View Details