PSMC5 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Proteasome (prosome, macropain) 26S subunit, ATPase, 5

Gene Aliases

S8, p45, RPT6, SUG1, SUG-1, TBP10, TRIP1, p45/SUG

Gene ID

5705

Swiss Prot

P62195

Accession Number

NP_002796

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5

Target

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.

Partner Proteins

HUWE1; KRT38; KRT40; PDCL; CIITA; FOS; THAP11; SUMO2; SUMO3; Gabbr2; PSMD14; UBE3C; UBC; PSMB4; RPS13; RPL29; PSMD12; PSMD11; PSMD8; PSMD3; PSMD1; PSMC6; DYNC1I2; ABCF1; KCMF1; UCHL5; KIAA0368; UBR4; ADRM1; MAP2; PARK2; FBXO6; RORA; PSMC4; BAG3; HIV2gp7

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK

Applications

IHC, IP, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

46kDa

Protein Length

406

NCBI Gene Symbol

PSMC5

Host or Source

Rabbit

Protein Name

26S protease regulatory subunit 8

Gene Name URL

PSMC5

Nucleotide Accession Number

NM_002805

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