IRF1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Interferon regulatory factor 1

Gene Aliases

MAR, IRF-1

Gene ID

3659

Swiss Prot

P10914

Accession Number

NP_002189

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of IRF1

Target

IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Partner Proteins

SUMO2; SUMO3; IRF2; KAT2B; EP300; PRDM1; UBC; BIRC3; MDM2; HIST1H3A; CBL; HSP90AA1; HSPA1A; Tbk1; STUB1; SPI1; QARS; IRF8; CDKN1B; TRIM28; SET; SP2; IRF9; YBX1; NPM1; TRMT2A; HCFC1; SEC63; KEAP1; TRAF3; CREBBP; tat; SMARCA4; STAT1; HMGA1; RELA; NFKB1; KAT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATW

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 86%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

36kDa

Protein Length

325

NCBI Gene Symbol

IRF1

Host or Source

Rabbit

Protein Name

Interferon regulatory factor 1

Gene Name URL

IRF1

Nucleotide Accession Number

NM_002198

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