HMGA1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

High mobility group AT-hook 1

Gene Aliases

HMG-R, HMGIY, HMGA1A

Gene ID

3159

Swiss Prot

Q5T6U8

Accession Number

NP_002122

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1

Target

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

NCOR2; UBE2I; PPARG; UBC; UPF2; HTT; OLA1; DNAJC8; PSIP1; METAP2; SYNCRIP; CWC27; HNRNPDL; EIF2S2; PCBP2; PCBP1; PA2G4; NPM1; NCL; HSPA1A; HNRNPL; HNRNPD; HNRNPAB; HNRNPA1; HMGB3; HMGB2; HMGB1; GTF2F2; XRCC6; CSNK2A1; RCC1; CDK1; APEX1; ANXA2; ANXA1; SSB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPKEPSEVPTPKRPRGRP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol