TRIM23 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Tripartite motif containing 23

Gene Aliases

ARD1, ARFD1, RNF46

Gene ID

373

Swiss Prot

P36406-3

Accession Number

NP_150231

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TRIM23

Target

TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Partner Proteins

LGALS8; TNFAIP3; TMSB4X; SNRPB; SNAI1; SNAI2; SIAH1; PSMA1; PIK3R2; PHF1; LMO2; FAM90A1; KRT6A; KIFC3; HOXB5; COX5B; CDR2; BAG1; TRIM23; AQP1; SLC25A6; FAM208B; FAM193B; ZNF581; SPG21; MRPL4; ARHGEF3; POLL; NFU1; GPKOW; HSPB7; PPIL2; TRIM29; DMC1; USP20

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKL

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

546

NCBI Gene Symbol

TRIM23

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase TRIM23

Gene Name URL

TRIM23

Nucleotide Accession Number

NM_033228

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