PAX6 Antibody - C-terminal region (ARP38063_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Paired box 6

Gene Aliases

AN, AN1, AN2, FVH1, MGDA, WAGR, ASGD5, D11S812E

Gene ID

5080

Swiss Prot

P26367

Accession Number

XP_005253013

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX6

Target

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

IPO13; Dlg4; NKIRAS2; Cacnb3; Pax6; Diap1; SMAD5; SMAD4; SMAD3; SMAD1; AR; HIPK2; SUMO1; SMARCA4; TP73; SHANK3; PBX1; VSX2; EN1; TRIM11; HOMER3; SIX3; INADL; EP300; SOX10; RGS3; DIAPH1; MAFG; RAX; DYNLL1; DLG1; CDX2; TBP; SOX3; MITF; HOXB1; SOX2; LHX2; TA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol