TADA2L Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcriptional adaptor 2A

Gene Aliases

ADA2, ADA2A, KL04P, hADA2, TADA2L

Gene ID

6871

Swiss Prot

O75478

Accession Number

NP_001479

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TADA2L

Target

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

MFAP1; MAGOH; KPNA2; FBF1; PRPF31; PPP1R16B; ZFYVE26; SF3A3; FARS2; MTX2; EIF4E2; FAM127C; KLHL38; TTC9C; ZNF564; TEKT4; LOC149950; KLC4; TTC23; GPSM3; CDCA7L; C1orf109; CCHCR1; PRKAB2; ARNT2; USP22; TADA3; HNF4A; LYN; HSP90AA1; KAT2B; MCPH1; PAXIP1; SUPT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LEYKSALLNECNKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

443

NCBI Gene Symbol

TADA2A

Host or Source

Rabbit

Protein Name

Transcriptional adapter 2-alpha

Gene Name URL

TADA2A

Nucleotide Accession Number

NM_001488

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