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Rorc antibody - N-terminal region (ARP37127_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

RAR-related orphan receptor gamma

Gene Aliases

Th, ROR, TOR, Thor, Nr1f3, RORgamma

Gene ID

19885

Swiss Prot

P51450

Accession Number

NP_035411

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Rorc is an orphan nuclear receptor. Isoform 2 negatively regulates expression of TNFSF6/FASL and IL2 production in T-cells. It also binds to the TEA promoter and may participate in the regulation of DNA accessibility in the TCR-Jalpha locus.

Partner Proteins

Cul3; Chd4; Ewsr1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VKFGRMSKKQRDSLHAEVQKQLQQQQQQEQVAKTPPAGSRGADTLTYTLG

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 85%; Guinea Pig: 79%; Human: 79%; Mouse: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

516

NCBI Gene Symbol

RORC

Host or Source

Rabbit

Protein Name

Nuclear receptor ROR-gamma

Gene Name URL

Rorc

Nucleotide Accession Number

NM_011281

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