Nkx3-1 Antibody - middle region (ARP37115_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
NK-3 transcription factor, locus 1 (Drosophila)
Gene Aliases
Ba, Bax, NKX, bag, NKX3., NKX3A, NKX3.1, Nkx-3., Nkx-3.1, bagpipe
Gene ID
18095
Swiss Prot
P97436
Accession Number
NP_035051
Reactivity
Mouse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Mouse Nkx3-1
Target
Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands) . It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
Partner Proteins
Fem1b; SP2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TPTEPESDAHFETYLLDCEHNPGDLASAPQVTKQPQKRSRAAFSHTQVIE
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Mouse: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
27kDa
Protein Length
237
NCBI Gene Symbol
NKX3-1
Host or Source
Rabbit
Protein Name
Homeobox protein Nkx-3.1
Gene Name URL
Nkx3-1
Nucleotide Accession Number
NM_010921
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