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Hira Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone cell cycle regulation defective homolog A (S. cerevisiae)

Gene Aliases

Tupl, N28177, Tuple1, Gm15797, AA138857, D16Ertd95, D16Ertd95e

Gene ID

15260

Swiss Prot

Q61666

Accession Number

NP_034565

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse Hira

Target

Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Partner Proteins

Nanog; Creb3l4; Crem; Pou5f1; Hirip3; Pax7; Pax3; H3f3b

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LRSRELESSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRPRKDSRL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 79%; Guinea Pig: 93%; Horse: 79%; Human: 86%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

112

Protein Length

1015

NCBI Gene Symbol

HIRA

Host or Source

Rabbit

Protein Name

Protein HIRA

Gene Name URL

Hira

Nucleotide Accession Number

NM_010435

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