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Tfam antibody - C-terminal region (ARP36993_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcription factor A, mitochondrial

Gene Aliases

Hmgt, mtTF, tsHM, Hmgts, mtTFA, tsHMG, AI661103

Gene ID

21780

Swiss Prot

P40630

Accession Number

NP_033386

Reactivity

Mouse, Rat, Cow, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of mouse Tfam

Target

TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.

Partner Proteins

C1QBP; SNCA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FQEAKDDSAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Mouse: 100%; Rabbit: 79%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

29 kDa

Protein Length

243

NCBI Gene Symbol

TFAM

Host or Source

Rabbit

Protein Name

Transcription factor A, mitochondrial

Gene Name URL

Tfam

Nucleotide Accession Number

NM_009360

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