MESP2 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Mesoderm posterior 2
Gene Aliases
BHLHc, bHLHc6
Gene ID
17293
Swiss Prot
O08574
Accession Number
NP_032615
Reactivity
Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Target
Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng) . It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Partner Proteins
Lfng
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
Applications
WB
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Mouse: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
41kDa
Protein Length
370
NCBI Gene Symbol
MESP2
Host or Source
Rabbit
Protein Name
Mesoderm posterior protein 2
Gene Name URL
MESP2
Nucleotide Accession Number
NM_008589
Curated Selection
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