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Irf1 antibody - C-terminal region (ARP36902_P050)

Product Specifications

Gene Name

Interferon regulatory factor 1

Gene Aliases

Irf, Irf-1, AU020929

Gene ID

16362

Swiss Prot

P15314

Accession Number

NP_032416

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and activates those genes. Irf1 acts as a tumor suppressor.

Partner Proteins

Ubc; Sumo1; Ube2i; Pias3; Tbk1; Polr2a

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HIDGKGYLLNEPGTQLSSVYGDFSCKEEPEIDSPRGDIGIGIQHVFTEMK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 90%; Dog: 80%; Guinea Pig: 86%; Human: 93%; Mouse: 100%; Rabbit: 86%; Rat: 93%; Sheep: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

37kDa

Protein Length

329

NCBI Gene Symbol

IRF1

Host or Source

Rabbit

Protein Name

Interferon regulatory factor 1

Gene Name URL

Irf1

CAS Number

9007-83-4

Nucleotide Accession Number

NM_008390

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