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CIITA Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Class II transactivator

Gene Aliases

C2t, C2ta, Gm9475, Mhc2ta, EG669998

Gene ID

12265

Swiss Prot

Q3U2P0

Accession Number

NP_031601

Reactivity

Human, Mouse, Rat, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of mouse C2TA

Target

This gene encodes a member of the NOD-like receptor protein family. This protein acts as a transcriptional coactivator and component of the enhanceosome complex to stimulate transcription of MHC class II genes in the adaptive immune response. This protein may also regulate the transcription of MHC class I genes. Mutations in the human gene have been linked to a rare immunodeficiency, bare lymphocyte syndrome, and homozygous knockout mice exhibit many features of this disease. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

Rfxank; Ssbp4; Ssbp3; Gmeb1; Cited4; Tcf3; Nfe2; Hoxa2; Ewsr1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MALWESLQQQGEAQLLQAAEEKFTIEPFKAKSPKDVEDLDRLVQTQRLRN

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Human: 79%; Mouse: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

119kDa

Protein Length

1078

NCBI Gene Symbol

CIITA

Host or Source

Rabbit

Protein Name

MHC class II transactivator

Gene Name URL

CIITA

Nucleotide Accession Number

NM_007575

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