ADAR antibody - C-terminal region (ARP36712_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Adenosine deaminase, RNA-specific

Gene Aliases

DSH, AGS6, G1P1, IFI4, P136, ADAR1, DRADA, DSRAD, IFI-4, K88DSRBP

Gene ID

103

Swiss Prot

P55265

Accession Number

NP_001102

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ADAR

Target

ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

UBC; SUMO2; SUMO3; STAU1; STAU2; SUMO1; RPA3; RPA2; RPA1; ERG; SUZ12; EED; EZH2; BMI1; RNF2; rev; FBXO6; TARDBP; UBE2I; HDAC9; XPO1; WHSC1; TGM2; SNRPN; SNRPB; UPF1; DHX9; DDX17; HNRNPM; CAND1; CUL3; HNRNPA1; ELAVL1; HDAC5; tat; ADAR; HDLBP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHR

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Guinea Pig: 92%; Horse: 92%; Human: 92%; Mouse: 91%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

136kDa

Protein Length

1226

NCBI Gene Symbol

ADAR

Host or Source

Rabbit

Protein Name

Double-stranded RNA-specific adenosine deaminase

Gene Name URL

ADAR

Nucleotide Accession Number

NM_001111

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