MCM5 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Minichromosome maintenance complex component 5

Gene Aliases

CDC46, MGORS8, P1-CDC46

Gene ID

4174

Swiss Prot

P33992

Accession Number

NP_006730

Reactivity

Human, Mouse, Rat, Cow, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5

Target

The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Partner Proteins

KRTAP10-7; RBPMS; SUMO2; SUMO3; MCMBP; UBC; RNF2; NEK9; MCM3; HSP90AB1; HSP90AA1; FKBP5; MAGED2; CAP1; BAG3; CD81; IGSF8; TCEA1; PNKP; VCAM1; ORC5; ORC1; MCM7; MCM2; ITGA4; FN1; CDKN2A; CDC5L; NOTCH1; MYBBP1A; U2AF1; MCM6; MCM4; HNRNPU; APP; FBXO6; NEDD8

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTG

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

82kDa

Protein Length

734

NCBI Gene Symbol

MCM5

Host or Source

Rabbit

Protein Name

DNA replication licensing factor MCM5

Gene Name URL

MCM5

Nucleotide Accession Number

NM_006739

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