WRNIP1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Werner helicase interacting protein 1

Gene Aliases

WHIP, FAP93, CFAP93, bA420G6.2

Gene ID

56897

Swiss Prot

Q96S55

Accession Number

NP_569079

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1

Target

Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.

Partner Proteins

UBC; RNF31; PIN1; ELP2; ELP3; TRIM28; HDAC11; EPAS1; VCP; SRSF4; SMAD2; RAD18; NUP107; WRNIP1; FGFR1OP; POLD1; ABL1; SUMO2; TOLLIP; DDX58; USP11; OSBPL10; USP25; POLD4; POLD2; WRN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPT

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%; Yeast: 77%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

72kDa

Protein Length

640

NCBI Gene Symbol

WRNIP1

Host or Source

Rabbit

Protein Name

ATPase WRNIP1

Gene Name URL

WRNIP1

Nucleotide Accession Number

NM_130395

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