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EIF4A3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Eukaryotic translation initiation factor 4A3

Gene Aliases

Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III

Gene ID

9775

Swiss Prot

P38919

Accession Number

NP_055555

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4A3

Target

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Partner Proteins

CDCA7L; PDCD4; HUWE1; POLDIP3; HAUS1; SUMO2; SUMO3; STAU1; UBC; LIN28B; SUMO1; WWOX; EED; RNF2; BMI1; SUZ12; ANP32A; PKM; NPLOC4; IPO11; PDLIM5; PLIN3; SRP14; RAD23B; AARS; FBXO6; SRPK2; SRPK1; UPF1; SMG1; RBM8A; ITGA4; CWC22; EEF2K; VCAM1; FN1; TRA2B; HN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 85%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

47kDa

Protein Length

411

NCBI Gene Symbol

EIF4A3

Host or Source

Rabbit

Protein Name

Eukaryotic initiation factor 4A-III

Gene Name URL

EIF4A3

Nucleotide Accession Number

NM_014740

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