SNRNP200 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Small nuclear ribonucleoprotein 200kDa (U5)

Gene Aliases

BRR2, RP33, HELIC2, ASCC3L1, U5-200KD

Gene ID

23020

Swiss Prot

O75643

Accession Number

NP_054733

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Target

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa.

Partner Proteins

PRPF8; EMD; CDKN1A; SUMO2; STAU1; UBC; SUMO1; LGR4; WWOX; RPA3; RPA2; RPA1; ERG; SUZ12; EZH2; EED; RNF2; rev; ELP3; KIAA1033; WDHD1; POLR2H; PIN1; USP34; TSC22D1; PARK2; FBXO6; TARDBP; PRPF4B; UBD; USP19; LSM8; SNRNP200; SF3B2; RBM5; ITGA4; FN1; RNF113A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKDLHPR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

244kDa

Protein Length

2136

NCBI Gene Symbol

SNRNP200

Host or Source

Rabbit

Protein Name

U5 small nuclear ribonucleoprotein 200 kDa helicase

Gene Name URL

SNRNP200

Nucleotide Accession Number

NM_014014

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