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DDX23 antibody - C-terminal region (ARP36377_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

Gene Aliases

Prp28, PRPF28, U5-100K, SNRNP100, U5-100KD

Gene ID

9416

Swiss Prot

Q9BUQ8

Accession Number

NP_004809

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Target

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing.

Partner Proteins

SUMO2; STAU1; UBC; RPA3; RPA2; RPA1; ERG; SUZ12; WBP4; PRPF4B; PAXIP1; PHF5A; SF3A3; SART1; THOC5; PURA; RNU6ATAC; RNU4ATAC; TERF2IP; TERF1; SIRT7; HNRNPA1; SF3A2; SUMO1; Prpf8; TOP1; SNW1; TP63; TP73; MEPCE; USP39; PRPF4; OTUB1; RNPS1; CD2BP2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLK

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

95kDa

Protein Length

820

NCBI Gene Symbol

DDX23

Host or Source

Rabbit

Protein Name

Probable ATP-dependent RNA helicase DDX23

Gene Name URL

DDX23

Nucleotide Accession Number

NM_004818

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