DDX23 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

Gene Aliases

Prp28, PRPF28, U5-100K, SNRNP100, U5-100KD

Gene ID

9416

Swiss Prot

Q9BUQ8

Accession Number

NP_004809

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DDX23

Target

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

Partner Proteins

SUMO2; STAU1; UBC; RPA3; RPA2; RPA1; ERG; SUZ12; WBP4; PRPF4B; PAXIP1; PHF5A; SF3A3; SART1; THOC5; PURA; RNU6ATAC; RNU4ATAC; TERF2IP; TERF1; SIRT7; HNRNPA1; SF3A2; SUMO1; Prpf8; TOP1; SNW1; TP63; TP73; MEPCE; USP39; PRPF4; OTUB1; RNPS1; CD2BP2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol