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AKAP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

A kinase (PRKA) anchor protein 1

Gene Aliases

AKAP, PRKA1, AKAP84, TDRD17, AKAP121, AKAP149, D-AKAP1, PPP1R43, SAKAP84

Gene ID

8165

Swiss Prot

Q92667

Accession Number

NP_644804

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AKAP1

Target

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP1 is a member of the AKAP family. It binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Partner Proteins

MDM2; PRKACB; PRKACA; UBC; APP; TP73; USP7; PPP1CA; MYCBP; PTPN21; CAV1; PRKAR1A; PRKAR2B; PRKAR1B; PRKAR2A; AMY1C; SIAH2; MAATS1; AMY1A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VPFSNGVLKGELSDLGAEDGWTMDAEADHSGVAAPPPGKRGTLITRCPGF

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

593

NCBI Gene Symbol

AKAP1

Host or Source

Rabbit

Protein Name

A-kinase anchor protein 1, mitochondrial

Gene Name URL

AKAP1

Nucleotide Accession Number

NM_139275

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