TOP5300
Product Specifications
UNSPSC Description
TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats[1].
Target Antigen
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/top5300.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C(C)(C)C)C)C1=NN(C2=C1COC3=C2C=C(C4=CN(CCO)N=C4)C(OC)=C3)C5=CC(Cl)=CC(Cl)=C5
Molecular Weight
570.47
References & Citations
[1]Nataraja S, et al. Discovery and Preclinical Development of Orally Active Small Molecules that Exhibit Highly Selective Follicle Stimulating Hormone Receptor Agonism. Front Pharmacol. 2021 Jan 14;11:602593.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160856/TOP5300-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160856/
Clinical Information
No Development Reported
CAS Number
1848981-48-5
Curated Selection
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