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NMI Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

N-myc (and STAT) interactor

Gene ID

9111

Swiss Prot

Q13287

Accession Number

NP_004679

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NMI

Target

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

HSPA8; GCSH; GOLGA8EP; HDDC3; C9orf72; TXLNA; TXLNB; CNKSR3; LCA5L; C1orf216; SFR1; TUBA3E; MTMR9; COPS7B; BRMS1; KDM1A; POMZP3; HHLA3; EMILIN1; SNAPC5; MAD2L1BP; NMI; MTMR6; SCEL; TRAF5; UBC; PSMG3; OXR1; EXOSC4; TOLLIP; CYHR1; VPS26A; H1FX; NAA10; TBCD

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQT

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

35kDa

Protein Length

307

NCBI Gene Symbol

NMI

Host or Source

Rabbit

Protein Name

N-myc-interactor

Gene Name URL

NMI

Nucleotide Accession Number

NM_004688

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