TRIP13 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Thyroid hormone receptor interactor 13

Gene Aliases

MVA3, OOMD9, 16E1BP

Gene ID

9319

Swiss Prot

Q15645

Accession Number

NP_004228

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIP13

Target

The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.

Partner Proteins

KRTAP26-1; KRTAP12-1; KRTAP12-2; MORN3; TEX37; METTL15; MGAT5B; C4orf33; GLYCTK; M1AP; LRR1; LNX1; RHOXF2; LOXL4; ZNF34; FNDC3B; TINAGL1; PBLD; SEMA4G; SPRYD7; PELI1; PLSCR3; PCMTD2; CYB5R2; AMDHD2; TNRC6A; DIP2A; DPYSL4; TRIP13; SIGLEC5; TPT1; SCP2; QARS

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEF

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

49kDa

Protein Length

432

NCBI Gene Symbol

TRIP13

Host or Source

Rabbit

Protein Name

Pachytene checkpoint protein 2 homolog

Gene Name URL

TRIP13

Nucleotide Accession Number

NM_004237

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