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LDB1 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

LIM domain binding 1

Gene Aliases

NLI, CLIM2, LDB-1, CLIM-2

Gene ID

8861

Swiss Prot

Q86U70-2

Accession Number

NP_003884

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDB1

Target

LDB1 binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. It may regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. It plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. And it acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. It acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.

Partner Proteins

LHX8; LHX6; SSBP3; LMO4; LMX1B; LMO2; LMO1; POLR1B; LSM7; IRAK3; UBC; PSMD10; PSMA1; TRIM33; ATXN1; RNF38; RNF6; rlim-a; RLIM; RB1; TAL1; LHX2; LMO3; SSBP4; SSBP2; TOLLIP; CTDSP1; LHX3; SSBP1; ISL1; LMX1A; ESR1; TCF3; SP1; CBFA2T3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPPSSQESKSENPT

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

41kDa

Protein Length

375

NCBI Gene Symbol

LDB1

Host or Source

Rabbit

Protein Name

LIM domain-binding protein 1

Gene Name URL

LDB1

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