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KCNQ5 Antibody - C-terminal region

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Product Specifications

Gene Name

Potassium voltage-gated channel subfamily Q member 5

Gene Aliases

Kv7.5, MRD46

Gene ID

56479

Swiss Prot

Q9NR82-3

Accession Number

NP_062816

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KCNQ5

Target

This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

KCNQ5; KCNQ3; DISC1; SRC; CALM3; CALM1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

103 kDa

Protein Length

942

NCBI Gene Symbol

KCNQ5

Host or Source

Rabbit

Protein Name

Potassium voltage-gated channel subfamily KQT member 5

Gene Name URL

KCNQ5

CAS Number

9007-83-4

Nucleotide Accession Number

NM_019842.3

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