α-Methyl-DL-aspartic acid
α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine[1].
Product Specifications
CAS Number
[2792-66-7]
UNSPSC
12352209
Hazard Statement
H315, H319
Target
Ser/Thr Protease
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-methyl-dl-aspartic-acid.html
Purity
99.93
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
CC(N)(C(O)=O)CC(O)=O
Molecular Formula
C5H9NO4
Molecular Weight
147.13
Precautions
H315, H319
References & Citations
[1]Asami Mori, et al. l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo. J Pharmacol Sci. 2015 Apr;127 (4) :419-23.|[2]Juliano R Guerreiro, et al. Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production. J Biol Chem. 2009 Jul 24;284 (30) :20022-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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