SCN7A Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Sodium voltage-gated channel alpha subunit 7

Gene Aliases

NaG, SCN6A, Nav2.1, Nav2.2

Gene ID

6332

Swiss Prot

Q01118

Accession Number

NP_002967.2

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human SCN7A

Target

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PFIYGNLSQGMVSEPLEDVDPYYYKKKNTFIVLNKNRTIFRFNAASILCT

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 79%; Guinea Pig: 80%; Human: 100%; Mouse: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

83kDa

Protein Length

762

NCBI Gene Symbol

SCN7A

Host or Source

Rabbit

Protein Name

Sodium channel protein type 7 subunit alpha

Gene Name URL

SCN7A

Nucleotide Accession Number

NM_002976.3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7105511-01 0.05 mg

ATP7A Antibody, FITC conjugated

Ask

View Details

MBS7105511-02 0.1 mg

ATP7A Antibody, FITC conjugated

Ask

View Details

MBS7105511-03 5x 0.1 mg

ATP7A Antibody, FITC conjugated

Ask

View Details

MBS9906228 Inquire

Goose Transcription Factor ETV7 (ETV7) ELISA Kit

Ask

View Details

EKU11210 96 Tests

Mouse Interleukin 9 (IL9) Mini sample ELISA Kit

Ask

View Details

031094-ML550 100 µL

LTB, CT (LTB, TNFC, TNFSF3, Lymphotoxin-beta, Tumor necrosis factor C, Tumor necrosis factor ligand superfamily member 3) (MaxLight 550) discontinued

Ask

View Details