What is the catalog number for CHRNB2 antibody - middle region (ARP34970_T100)?

The catalog number for CHRNB2 antibody - middle region (ARP34970_T100) is ARP34970_T100.

What sizes are available for CHRNB2 antibody - middle region (ARP34970_T100)?

CHRNB2 antibody - middle region (ARP34970_T100) is available in the following size(s): 100 µL.

Is CHRNB2 antibody - middle region (ARP34970_T100) in stock?

CHRNB2 antibody - middle region (ARP34970_T100) is currently made to order / not held in immediate stock. Contact us for lead time.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

CHRNB2 antibody - middle region (ARP34970_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

Cholinergic receptor, nicotinic, beta 2 (neuronal)

Gene Aliases

EFNL3, nAChRB2

Gene ID

1141

Swiss Prot

P17787

Accession Number

NP_000739

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2

Target

Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.

Partner Proteins

CRELD2; CHRNA4; CHRNA2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWD

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol