SCNN1B Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Sodium channel, non-voltage-gated 1, beta subunit

Gene Aliases

BESC1, ENaCb, SCNEB, LIDLS1, ENaCbeta

Gene ID

6338

Swiss Prot

P51168

Accession Number

NP_000327

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B

Target

When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.

Partner Proteins

NEDD4L; SERP1; SCNN1G; SCNN1A; COMMD1; UBC; USP2; RAF1; NEDD4; TSC22D3; SGK1; EPN1; AP1M2; NFASC; CNTN1; WWP2; SCNN1D; ANK3; STX1A; ITCH; HECW1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

70kDa

Protein Length

640

NCBI Gene Symbol

SCNN1B

Host or Source

Rabbit

Protein Name

Amiloride-sensitive sodium channel subunit beta

Gene Name URL

SCNN1B

Nucleotide Accession Number

NM_000336

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