Vitamin K1
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
Product Specifications
CAS Number
84-80-0
Product Name Alternative
Phylloquinone; Phytomenadione
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Vitamin_K1.html
Purity
98.60
Solubility
DMSO : 6.67 mg/mL (ultrasonic) |Ethanol : ≥ 50 mg/mL
Smiles
O=C1C(C)=C(C/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(C2=C1C=CC=C2)=O
Molecular Formula
C31H46O2
Molecular Weight
450.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Basset GJ, et al. Phylloquinone (Vitamin K1) : Occurrence, Biosynthesis and Functions. Mini Rev Med Chem. 2016 Jun 22.|[2]Orlando A, et al. Vitamin K1 exerts antiproliferative effects and induces apoptosis in three differently graded human colon cancer cell lines. Biomed Res Int. 2015;2015:296721.|[3]Ibarrola-Jurado N, et al. Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease. Am J Clin Nutr. 2012 Nov;96 (5) :1113-8.|[4]Kim M, et al. Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice. J Clin Biochem Nutr. 2013 Sep;53 (2) :108-13.|[5]Hemmati AA, et al. Topical vitamin K1 promotes repair of full thickness wound in rat. Indian J Pharmacol. 2014 Jul-Aug;46 (4) :409-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Available Sizes
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