Vitamin K1

Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

Product Specifications

CAS Number

[84-80-0]

Product Name Alternative

Phylloquinone; Phytomenadione

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Vitamin_K1.html

Purity

98.60

Solubility

DMSO : 6.67 mg/mL (ultrasonic) |Ethanol : ≥ 50 mg/mL

Smiles

O=C1C(C)=C(C/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(C2=C1C=CC=C2)=O

Molecular Formula

C31H46O2

Molecular Weight

450.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Basset GJ, et al. Phylloquinone (Vitamin K1) : Occurrence, Biosynthesis and Functions. Mini Rev Med Chem. 2016 Jun 22.|[2]Orlando A, et al. Vitamin K1 exerts antiproliferative effects and induces apoptosis in three differently graded human colon cancer cell lines. Biomed Res Int. 2015;2015:296721.|[3]Ibarrola-Jurado N, et al. Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease. Am J Clin Nutr. 2012 Nov;96 (5) :1113-8.|[4]Kim M, et al. Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice. J Clin Biochem Nutr. 2013 Sep;53 (2) :108-13.|[5]Hemmati AA, et al. Topical vitamin K1 promotes repair of full thickness wound in rat. Indian J Pharmacol. 2014 Jul-Aug;46 (4) :409-12.