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RRN3 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)

Gene Aliases

TIFIA, A-270G1.2

Gene ID

54700

Swiss Prot

Q9NYV6

Accession Number

NP_060897

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Target

In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.

Partner Proteins

UBC; ACTA1; Polr1e; POLR1B; EIF3L; NMI; RBM15; UBD; Trim28; ELAVL1; TAF1D; POLR1A; MYO1C; TAF1C; TAF1B; TAF1A; UBTF; TBP; PPP2R2A; CDK2; CCNE1; RIBIN; ACTB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VDGKVDNGKTKDLYRDLINIFDKLLLPTHASCHVQFFMFYLCSFKLGFAE

Applications

WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

74kDa

Protein Length

650

NCBI Gene Symbol

RRN3

Host or Source

Rabbit

Protein Name

RNA polymerase I-specific transcription initiation factor RRN3

Gene Name URL

RRN3

Nucleotide Accession Number

NM_018427

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