TRIM24 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Tripartite motif containing 24

Gene Aliases

PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA

Gene ID

8805

Swiss Prot

O15164

Accession Number

NP_056989

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRIM24

Target

The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Partner Proteins

UBC; SUMO2; SUMO3; TRIM33; TP53; SUMO1; RNF2; RNF181; RNF141; ESR2; BRCA1; SF3B1; SF3B2; SNRPA; NONO; CDK12; NCOA1; TRIM8; NR3C2; ESR1; HIST1H3E; HIST2H4B; HIST4H4; HIST1H3F; HIST2H4A; HIST1H4L; HIST1H4E; HIST1H4B; HIST1H4H; HIST1H4C; HIST1H4J; HIST1H4K

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

117kDa

Protein Length

1050

NCBI Gene Symbol

TRIM24

Host or Source

Rabbit

Protein Name

Transcription intermediary factor 1-alpha

Gene Name URL

TRIM24

Nucleotide Accession Number

NM_015905

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