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CHD4 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Chromodomain helicase DNA binding protein 4

Gene Aliases

CHD-4, Mi-2b, SIHIWES, Mi2-BETA

Gene ID

1108

Swiss Prot

Q14839

Accession Number

NP_001264

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHD4

Target

CHD4 is a probable transcription regulator.The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SUMO2; SUMO3; DNMT3B; DNMT1; NACC2; UBC; LGR4; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; BMI1; GATAD2A; HDAC2; HDAC1; MTA3; CSNK2A1; HIST3H3; VCAM1; ITGA4; NOTCH1; ESR1; TBL1XR1; MBD3; MTA2; SMARCC1; RBBP7; RBBP4; CHD3; SNAI1; SNAI2; SUMO1; NEDD8; MTA1; NR2C2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

218kDa

Protein Length

1912

NCBI Gene Symbol

CHD4

Host or Source

Rabbit

Protein Name

Chromodomain-helicase-DNA-binding protein 4

Gene Name URL

CHD4

Nucleotide Accession Number

NM_001273

Frequently Asked Questions

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