AFDN Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Afadin, adherens junction formation factor

Gene Aliases

AF6, MLLT4, MLL-AF6, l-afadin

Gene ID

4301

Swiss Prot

P55196

Accession Number

EAW47480

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4

Target

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t (6;11) (q27; q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

Partner Proteins

UBC; LGR4; LATS2; YWHAQ; YWHAE; VCAM1; SMAD2; ITGA4; GRB2; FN1; SIRT7; HNRNPA1; ARRB2; YWHAG; YWHAB; KMT2A; MEN1; PVRL4; PICK1; RIT2; SORBS2; F11R; NRXN2; SSX2IP; RIT1; NRXN3; PVRL3; PVRL1; MRAS; SORBS1; EPHB6; EPHA7; JAG1; EPHB3; RALGDS; TJP1; EPHB2; PVR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAE

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol