MLLT4 antibody - N-terminal region (ARP34225_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

Afadin, adherens junction formation factor

Gene Aliases

AF6, MLLT4, MLL-AF6, l-afadin

Gene ID

4301

Swiss Prot

P55196

Accession Number

EAW47480

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4

Target

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t (6;11) (q27; q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

Partner Proteins

UBC; LGR4; LATS2; YWHAQ; YWHAE; VCAM1; SMAD2; ITGA4; GRB2; FN1; SIRT7; HNRNPA1; ARRB2; YWHAG; YWHAB; KMT2A; MEN1; PVRL4; PICK1; RIT2; SORBS2; F11R; NRXN2; SSX2IP; RIT1; NRXN3; PVRL3; PVRL1; MRAS; SORBS1; EPHB6; EPHA7; JAG1; EPHB3; RALGDS; TJP1; EPHB2; PVR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAE

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 85%; Rat: 100%; Yeast: 92%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

74kDa

Protein Length

674

NCBI Gene Symbol

AFDN

Host or Source

Rabbit

Protein Name

Afadin

Gene Name URL

AFDN

Nucleotide Accession Number

NM_001040000

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