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ATF2 Antibody - C-terminal region

Product Specifications

Gene Name

Activating transcription factor 2

Gene Aliases

HB16, CREB2, TREB7, CREB-2, CRE-BP1

Gene ID

1386

Swiss Prot

P15336-2

Accession Number

NP_001871

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2

Target

ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

Partner Proteins

MAPK10; MAPK9; MAPK8; MAPK1; SUMO1; KIFC3; FOS; MAPK14; EXOSC8; JUN; CREBBP; ATF2; CEBPG; BACH1; ATF4; ATF3; BATF3; DDIT3; BATF; FOSL1; H2AFY; RB1; GAPDH; NME2P1; TUBB; SFXN1; RAB2B; TMX1; GRPEL1; COLGALT1; AHNAK; SQRDL; RTN4; APMAP; C19orf10; RAB14; ERO1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTE

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

55kDa

Protein Length

505

NCBI Gene Symbol

ATF2

Host or Source

Rabbit

Protein Name

Cyclic AMP-dependent transcription factor ATF-2

Gene Name URL

ATF2

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001880

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