G22P1 antibody - N-terminal region (ARP34117_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

X-ray repair complementing defective repair in Chinese hamster cells 6

Gene Aliases

ML8, KU70, TLAA, CTC75, CTCBF, G22P1

Gene ID

2547

Swiss Prot

Q6FG89

Accession Number

NP_001460

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1

Target

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Partner Proteins

UBC; ELF3; EHF; CHD1L; SUMO2; SUMO3; MDM2; EMD; ATRX; RPA3; RPA2; RPA1; PCNA; EED; PRPF40A; SUPT5H; ST13; SET; PLOD2; PIN1; NARS; MSH2; RPSA; JUP; IMPDH1; MSH6; GART; DPYSL3; CTNNA1; SAMHD1; ATP6V1B2; GANAB; SWAP70; WBP4; HYOU1; FARSB; RANBP3; CUL2; CSDE1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVL

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol