Anti-UBE2N

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin-conjugating enzyme E2N

Gene Aliases

UBC13, UbcH13, HEL-S-71, UbcH-ben, UBCHBEN; UBC13

Gene ID

7334

Swiss Prot

P61088

Accession Number

NP_003339

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UBE2N

Target

UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.

Partner Proteins

TRIM33; BFAR; MALT1; STUB1; BCL10; UBE2V2; UBC; TRAF6; ZNRF1; XIAP; SLX8; SLX5; MARCH7; TNF; UBE2N; RNF168; RNF8; PARK2; OTUB1; ARIH1; NEDD4L; MFN2; TRIM72; PELI3; RNF111; RNF11; BAG3; TRAF2; FN1; VCAM1; RNF126; RNF115; NBN; ATP6V1H; VPS33B; ZDHHC5; ACTR2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQW

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

17kDa

Protein Length

152

NCBI Gene Symbol

UBE2N

Host or Source

Rabbit

Protein Name

Ubiquitin-conjugating enzyme E2 N

Gene Name URL

UBE2N

Nucleotide Accession Number

NM_003348

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