KCNA5 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Potassium voltage-gated channel, shaker-related subfamily, member 5

Gene Aliases

HK2, HCK1, PCN1, ATFB7, HPCN1, KV1.5

Gene ID

3741

Swiss Prot

P22460

Accession Number

NP_002225

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5

Target

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.

Partner Proteins

SIRT1; KCNAB2; ERBB2IP; SNTA1; HSP90AA1; TNK2; Rab11a; DCTN2; GNB2L1; KCNAB1; TFRC; SRC; PRKCQ; PRKCB; KCNA5; KCNA4; KCNA3; KCNA2; FYN; FHL1; DYNC1I1; CAV1; ACTN2; UBE2I; SUMO3; RAB5A; RAB4A; DLG4; DLG1; PTPRE

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

67kDa

Protein Length

613

NCBI Gene Symbol

KCNA5

Host or Source

Rabbit

Protein Name

Potassium voltage-gated channel subfamily A member 5

Gene Name URL

KCNA5

Nucleotide Accession Number

NM_002234

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx327795-01 50 µg

Dual Specificity Phosphatase 10 (DUSP10) Antibody

Ask

View Details

abx327795-02 100 µg

Dual Specificity Phosphatase 10 (DUSP10) Antibody

Ask

View Details

GTR15188962 1 Vial

Lentiviral mouse Ntf3 shRNA (UAS) - Lentiviral mouse Ntf3 shRNA (UAS, GFP) plasmid

Ask

View Details

MBS1019812 Inquire

Recombinant Pasteurella multocida 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (metE), partial

Ask

View Details

TA349881 100 µL

DDX19B Rabbit Polyclonal Antibody

Ask

View Details

QM30402S 200 Tests

Mouse Syt9 qPCR Primer Pair

Ask

View Details