KCNA5 antibody - N-terminal region (ARP33977_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Potassium voltage-gated channel, shaker-related subfamily, member 5

Gene Aliases

HK2, HCK1, PCN1, ATFB7, HPCN1, KV1.5

Gene ID

3741

Swiss Prot

P22460

Accession Number

NP_002225

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5

Target

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.

Partner Proteins

SIRT1; KCNAB2; ERBB2IP; SNTA1; HSP90AA1; TNK2; Rab11a; DCTN2; GNB2L1; KCNAB1; TFRC; SRC; PRKCQ; PRKCB; KCNA5; KCNA4; KCNA3; KCNA2; FYN; FHL1; DYNC1I1; CAV1; ACTN2; UBE2I; SUMO3; RAB5A; RAB4A; DLG4; DLG1; PTPRE

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol