TNKS antibody - middle region (ARP33756_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Gene Aliases

TIN1, ARTD5, PARPL, TINF1, TNKS1, pART5, PARP5A, PARP-5a

Gene ID

8658

Swiss Prot

O95271

Accession Number

NP_003738

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TNKS

Target

TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.

Partner Proteins

RNF146; RAPGEF2; TINF2; TNKS; TERF1; SH3BP2; APC; BLZF1; GMDS; UBC; DISC1; TNIK; SH3BP5; TERF2; FANCD2; BABAM1; VPS33A; FNBP1; MCL1; POT1; TNKS2; TNKS1BP1; NUMA1; LNPEP

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQST

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

142kDa

Protein Length

1327

NCBI Gene Symbol

TNKS

Host or Source

Rabbit

Protein Name

Tankyrase-1

Gene Name URL

TNKS

Nucleotide Accession Number

NM_003747

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