CIR antibody - middle region (ARP33737_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Corepressor interacting with RBPJ, 1

Gene Aliases

CIR

Gene ID

9541

Swiss Prot

Q86X95

Accession Number

EAX11146

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CIR

Target

CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC) . CIR is also required for RBPSUH-mediated repression of transcription.

Partner Proteins

CEP76; NEK6; U2AF1; SRSF2; SRSF1; RP9; HDAC2; SAP30; SNW1; TCEA1; NCOR2; RBPJ

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

324

NCBI Gene Symbol

CIR1

Host or Source

Rabbit

Protein Name

Corepressor interacting with RBPJ 1

Gene Name URL

CIR1

Nucleotide Accession Number

Q86X95

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