TCF7L2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcription factor 7-like 2 (T-cell specific, HMG-box)

Gene Aliases

TCF4, TCF-4

Gene ID

6934

Swiss Prot

Q6FHW4

Accession Number

NP_110383

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TCF7L2

Target

The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605

Partner Proteins

UBC; FBLN1; UBE2I; PSMA3; MAD2L2; ZBTB33; DAXX; CTNNB1; ELAVL1; PARP1; XRCC5; SUMO2; XRCC6; NR5A1; EP300; CEBPA; CTBP1; DAZAP2; CTNNBIP1; JUP; CSNK2A2; CSNK2A1; PSEN1; NLK; RAC1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 92%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

596

NCBI Gene Symbol

TCF7L2

Host or Source

Rabbit

Protein Name

TCF7L2 protein EMBL CAG38811.1

Gene Name URL

TCF7L2

Nucleotide Accession Number

NM_030756

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

sc-236606 10 g

(R) - (+) -Lactamide

Ask

View Details

TR510820 1 Kit

Arf2 Mouse shRNA Plasmid (Locus ID 11841)

Ask

View Details

MBS7185575 Inquire

Rabbit anti-Escherichia coli (strain SMS-3-5/SECEC) LSRF Polyclonal Antibody

Ask

View Details

300226 5 mg

Epigomisin O

Ask

View Details