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FLJ11730 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

MYST/Esa1-associated factor 6

Gene Aliases

EAF6, CENP-28, C1orf149, NY-SAR-91

Gene ID

64769

Swiss Prot

Q86WE3

Accession Number

NP_073593

Reactivity

Human, Mouse, Rat, Cow, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FLJ11730

Target

The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synoivial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens. Sarcoma antigen NY-SAR-91 is one of them.

Partner Proteins

PLEKHF2; TRIM54; LDOC1; UBC; FXR2; H2AFZ; ELAVL1; SUMO2; JADE1; KAT5; tat; MRGBP; ING5; KAT6A; BRPF1; CCDC85B; L3MBTL2; ING3; ING4; KAT7

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQM

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

201

NCBI Gene Symbol

MEAF6

Host or Source

Rabbit

Protein Name

Chromatin modification-related protein MEAF6

Gene Name URL

MEAF6

Nucleotide Accession Number

NM_022756

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