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C20ORF20 antibody - middle region (ARP33352_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Chromosome 20 open reading frame 20

Gene Aliases

Eaf7, URCC4, MRG15BP, C20orf20

Gene ID

55257

Swiss Prot

Q9NV56

Accession Number

NP_060740

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20

Target

C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Partner Proteins

MORF4L1; MORF4L2; NOTCH2NL; KRTAP10-7; H2AFZ; ELAVL1; SH3BP4; VAV2; UBC; H2AFV; MRFAP1; EPC1; DMAP1; MRGBP; MBTD1; EPC2; SIN3B; BRD8; RUVBL2; SRCAP; KAT5; RUVBL1; HIST2H2BE; TUBA1A; TUBB2A; RBBP7; HNRNPM; LMNA; KPNA2; KPNB1; HSPA4; HNRNPU; HNRNPK; ACTL6A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEM

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

22kDa

Protein Length

204

NCBI Gene Symbol

MRGBP

Host or Source

Rabbit

Protein Name

MRG-binding protein

Gene Name URL

MRGBP

Nucleotide Accession Number

NM_018270

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