IVNS1ABP Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Influenza virus NS1A binding protein

Gene Aliases

ND1, ARA3, NS-1, IMD70, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068

Gene ID

10625

Swiss Prot

Q9Y6Y0

Accession Number

NP_006460

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IVNS1ABP

Target

This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.

Partner Proteins

UBC; DHX36; PARP1; ACTB; ZC3HAV1; RBMX; LARP1; DHX30; HNRNPUL1; IGF2BP1; IVNS1ABP; DDX17; HNRNPR; LRPPRC; THRAP3; G3BP2; DDX21; PABPC4; GBF1; STAU1; UPF1; POLR2A; YBX1; NCBP1; HNRNPM; MYH9; ILF3; ILF2; HSP90AB1; HSPA8; HNRNPU; HNRNPL; HNRNPK; HNRNPF; HNRN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

72kDa

Protein Length

642

NCBI Gene Symbol

IVNS1ABP

Host or Source

Rabbit

Protein Name

Influenza virus NS1A-binding protein

Gene Name URL

IVNS1ABP

Nucleotide Accession Number

NM_006469

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